Dark spots, melasma, and post-acne marks that won't fade need more than one brightening ingredient. This ampoule combines four natural melanin inhibitors — Kojic Acid, Arbutin, Bearberry, and Mulberry Extract — each working through a different biochemical pathway to suppress pigmentation comprehensively.

100 percent hydroquinone-free, with none of the irritation or rebound darkening that synthetic alternatives cause. Kojic Acid inhibits tyrosinase directly. Arbutin blocks melanin synthesis at a different enzymatic step. Bearberry and Mulberry suppress melanin transfer to skin cells. Together, they interrupt the pigmentation process at four separate points — which is why this ampoule delivers the kind of visible results that single-ingredient brightening products can't match. Bio Jouvance Paris formulated this as the natural depigmentation protocol trusted by professionals worldwide.

Hero Ingredients and Their Benefits:

• Kojic Acid: Derived from Japanese Koji mushroom fermentation, directly inhibits the tyrosinase enzyme responsible for melanin production at its source.
• Arbutin: A naturally occurring melanin inhibitor that blocks melanin synthesis through a different enzymatic pathway than Kojic Acid, amplifying the brightening effect.
• Bearberry and Mulberry Extracts: Suppress the transfer of melanin granules to skin cells, preventing new pigmentation from reaching the visible surface.

How to Use:

Apply the ampoule to clean skin. Massage the face, neck, and decollete using gentle, upward strokes for one to two minutes. Apply the Depigmentation Leave-On Masque on top to seal the beneficial ingredients into the skin and extend the brightening treatment.

Complete Your Treatment:

Pair with the Depigmentation Peel-Off Masque or the Skin Lightening Serum between professional appointments to maintain and extend the depigmentation results.